Ruxolitinib As An Adjunctive Treatment To Reduce Inflammatory Responses In Malaria: A Randomized Placebo Controlled Trial In Volunteers Experimentally Infected With Plasmodium Falciparum

Bridget E Barber; Rebecca Webster; Nischal Sahai; Indika Leelasena; Eniko Ujvary; Sue Mathison; Luzia Bukali; Damian A Oyong; Fabian de Labastida Rivera; Jessica Engel; Dean W Andrew; Megan S F Soon; Nicholas L Dooley; Jessica R Loughland; Jeremy Gower; Jenny M Peters; Ria Woo; Adam J. Potter; Stacey Llewellyn; Fiona H Amante; Teija Frame; Julianne Hamelink; Mayimuna Nalubega; Reena Mukhiya; James S McCarthy; Christian R Engwerda; Michelle J Boyle

doi:10.4269/ajtmh.abstract2024

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Ruxolitinib As An Adjunctive Treatment To Reduce Inflammatory Responses In Malaria: A Randomized Placebo Controlled Trial In Volunteers Experimentally Infected With Plasmodium Falciparum

Abstract

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Ruxolitinib As An Adjunctive Treatment To Reduce Inflammatory Responses In Malaria: A Randomized Placebo Controlled Trial In Volunteers Experimentally Infected With Plasmodium Falciparum

Bridget E Barber, Rebecca Webster, Nischal Sahai, Indika Leelasena, Eniko Ujvary, Sue Mathison, Luzia Bukali, Damian A Oyong, Fabian de Labastida Rivera, Jessica Engel, …

American Journal of Tropical Medicine and Hygiene, Vol.112(6, Supplement), 6829

American Society of Tropical Medicine & Hygiene (ASTMH) Annual Meeting, 2024 (New Orleans, United States, 13-Nov-2024–17-Nov-2024)

2026

DOI: https://doi.org/10.4269/ajtmh.abstract2024

Abstract

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Title: Ruxolitinib As An Adjunctive Treatment To Reduce Inflammatory Responses In Malaria: A Randomized Placebo Controlled Trial In Volunteers Experimentally Infected With Plasmodium Falciparum
Authors: Bridget E Barber - QIMR Berghofer Medical Research Institute
Rebecca Webster - QIMR Berghofer Medical Research Institute
Nischal Sahai - University of the Sunshine Coast
Indika Leelasena - University of the Sunshine Coast
Eniko Ujvary - University of the Sunshine Coast
Sue Mathison - University of the Sunshine Coast
Luzia Bukali - QIMR Berghofer Medical Research Institute
Damian A Oyong - Burnet Institute
Fabian de Labastida Rivera - QIMR Berghofer Medical Research Institute
Jessica Engel - QIMR Berghofer Medical Research Institute
Dean W Andrew - QIMR Berghofer Medical Research Institute
Megan S F Soon - QIMR Berghofer Medical Research Institute
Nicholas L Dooley - Burnet Institute
Jessica R Loughland - QIMR Berghofer Medical Research Institute
Jeremy Gower - QIMR Berghofer Medical Research Institute
Jenny M Peters - QIMR Berghofer Medical Research Institute
Ria Woo - QIMR Berghofer Medical Research Institute
Adam J. Potter - QIMR Berghofer Medical Research Institute
Stacey Llewellyn - QIMR Berghofer Medical Research Institute
Fiona H Amante - QIMR Berghofer Medical Research Institute
Teija Frame - QIMR Berghofer Medical Research Institute
Julianne Hamelink - QIMR Berghofer Medical Research Institute
Mayimuna Nalubega - QIMR Berghofer Medical Research Institute
Reena Mukhiya - Burnet Institute
James S McCarthy - The University of Melbourne
Christian R Engwerda - QIMR Berghofer Medical Research Institute
Michelle J Boyle - Burnet Institute
Publication details: American Journal of Tropical Medicine and Hygiene, Vol.112(6, Supplement), 6829
Conference details: American Society of Tropical Medicine & Hygiene (ASTMH) Annual Meeting, 2024 (New Orleans, United States, 13-Nov-2024–17-Nov-2024)
Publisher: American Society of Tropical Medicine and Hygiene
Date published: 2026
DOI: 10.4269/ajtmh.abstract2024
ISSN: 1476-1645
Organisation Unit: UniSC Clinical Trials Centre
Language: English
Record Identifier: 991216248202621
Output Type: Abstract

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Collaboration types: Domestic collaboration
Web Of Science research areas: Public, Environmental & Occupational Health; Tropical Medicine