Influence of age on arterial stiffness responses following a short period of sitting in healthy males

C Askew; T Bailey; K Doma; A Leicht; M Perissiou; D Pierce; M Windsor

doi:10.1016/j.jsams.2021.09.043

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Influence of age on arterial stiffness responses following a short period of sitting in healthy males

Abstract

Peer reviewed

Influence of age on arterial stiffness responses following a short period of sitting in healthy males

C Askew, T Bailey, K Doma, A Leicht, M Perissiou, D Pierce and M Windsor

Journal of Science and Medicine in Sport, Vol.24(Supplement 1), pp.S13-S14

SMA e-Conference

2021

DOI: https://doi.org/10.1016/j.jsams.2021.09.043

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Abstract

Background: Age-related increases in arterial stiffness including carotid-femoral pulse wave velocity (cf-PWV), aortic wave reflection via augmentation index (AIx) and reflection magnitude (RM) have been associated with future cardiovascular event risk. Chronic or prolonged inactivity has been reported to exacerbate the age-related increases in arterial stiffness. However, little is known about the impact of a short, period of inactivity on arterial stiffness with age potentially an influencing factor. The aim of this study was to examine the effect of age on the acute, arterial stiffness responses following a short period of sitting in healthy males. Methods: Twenty-two young (27.1±7.3 yrs, 177.4±5.4 cm,82.2±10.2 kg, 26.1±3.1 kg.m-2) and twenty-two older (68.8±5.3 yrs 174.6±7.6 cm, 77.7±7.0 kg, 25.6±3.0 kg.m-2) males volunteered. Supine, resting measures of cf-PWV, AIx corrected to a heart rate of 75(AIx75) and RM were obtained prior to (baseline), and 20-, 40- and 60-minutes following a short period of sitting (24-30 minutes). Heart rate(HR), systolic (SBP), diastolic (DBP) and mean arterial (MAP) blood pressure were recorded throughout the sitting period. Significant (pb0.05)differences over time and between groups were examined by 2-wayANOVA and post-hoc, pairwise comparisons with Bonferroni correction. Results: During the short period of sitting, lower HR (53.9±8.0 vs.64.6±7.7 bpm, pb0.001) and greater peripheral SBP (131.2±13.1 vs.118.8±9.6 mmHg, pb0.001), DBP (79.9±8.7 vs. 74.7±6.4 mm Hg,p=0.027) and MAP (97.0±9.2 vs. 89.4±7.0 mmHg, p=0.003) were observed in the older compared to the young group. The older group exhibited significantly greater resting cf-PWV(9.0±1.4vs. 7.3±0.9 m.s-1, pb0.001), AIx75 (12.6±9.2 vs. 4.0±14.0 %, p=0.011) and RM(73.6±14.0 vs. 59.0±12.4 %, pb0.001), and lower HR (48.9±6.4 vs.55.0±7.7 bpm, p=0.002) compared to the young group. Compared to baseline, cf-PWV was significantly increased at 60-minutes after the sitting period (pb0.05) with the change being similar between groups (p=0.792). In contrast, AIx75 and RM were significantly decreased at 40- and 60-minutes after sitting (pb0.05) with the change being similar between groups (pN0.05). Discussion: A short period of sitting resulted in a significant increase in central arterial stiffness(cf-PWV) and a concurrent decrease in peripheral arterial stiffness (AIx75 and RM) with these responses being unaffected by age in healthy males. The current results extend previous work that sitting, even for a short period, may progressively contribute to changes in central and peripheral arterial stiffness and future cardiovascular event risk. "My co-authors and I acknowledge that we have no conflict of interest of relevance to the submission of this abstract."

Details

Title: Influence of age on arterial stiffness responses following a short period of sitting in healthy males
Authors: C Askew (Author) - University of the Sunshine Coast, Queensland, School of Health and Behavioural Sciences - Legacy
T Bailey (Author) - University of Queensland
K Doma (Author) - James Cook University
A Leicht (Author) - James Cook University
M Perissiou (Author) - University of Portsmouth
D Pierce (Author) - James Cook University
M Windsor (Author) - University of the Sunshine Coast, Queensland, School of Health and Behavioural Sciences - Legacy
Publication details: Journal of Science and Medicine in Sport, Vol.24(Supplement 1), pp.S13-S14
Conference details: SMA e-Conference
Publisher: Elsevier Australia
Date published: 2021
DOI: 10.1016/j.jsams.2021.09.043
ISSN: 1878-1861
Organisation Unit: School of Health and Sport Sciences - Legacy; School of Health - Sports & Exercise Science; University of the Sunshine Coast, Queensland; School of Health and Behavioural Sciences - Legacy; UniSC Clinical Trials Centre; Cancer Research Cluster
Language: English
Record Identifier: 99585608602621
Output Type: Abstract

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