Logo image
Back
25-hydroxyvitamin D and parathyroid hormone: association with metabolic syndrome in black South-African women
Abstract   Open access   Peer reviewed

25-hydroxyvitamin D and parathyroid hormone: association with metabolic syndrome in black South-African women

O F Sotunde, H S Kruger, Hattie H Wright, L Havemann-Nel, Carina M C Mels, C Ravyse and M Pieters
South African Journal of Clinical Nutrition, Vol.29(3), pp.S21-S22
Nutrition Congress: Science at the centre of sound nutrition, 2016 (Somerset West, South Africa, 03-Sep-2016–05-Sep-2016)
2016
pdf
PDF - Published Version (Open Access)419.38 kBDownloadView
Published VersionPDF - Published Version (Open Access)CCBY-NC-ND_V2.5,  Open Access
url
http://sajcn.redbricklibrary.com/index.php/SAJCN/article/download/1142/1458View
Webpage

Abstract

Nutrition and Dietetics 25(OH)D PTH adiposity obesity metabolic syndrome black South African women
Introduction: The relationship between 25 hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH) and metabolic traits appear to differ among ethnicities and may be infl uenced by excess adiposity. Aim: To examine the association of serum 25(OH)D and PTH, respectively, with the metabolic syndrome (MetS) while controlling for adiposity in black women. Methods: A cross-sectional study was carried out among 209 urban black women aged ≥43 years from the North West Province, South Africa. The relationship between 25(OH)D, PTH and body composition were explored using multiple regression models. To explore the association between 25(OH)D, PTH and MetS, a separate variable was created including at least three of the MetS criteria, but excluding elevated waist circumference as a diagnostic criterion in a logistic regression model. Results: Majority (69.9%) of the women were overweight or obese and 65.5% had excessive adiposity using the age specifi c cut-off points for body fat percentage. BMI and waist circumference, but not body fat % had negative associations with 25(OH)D, while all body composition variables were positively associated with PTH, also after adjusting for confounders. Before and after adjusting for age, body fat, habitual physical activity, tobacco use, season of data collection and estimated glomerular fi ltration rate, neither 25(OH)D nor PTH showed signifi cant associations with the MetS. Conclusions: Although 25(OH)D was negatively and PTH was positively associated with adiposity variables in black women, there was no association between either 25(OH)D or PTH and the MetS in this study population, nor did adiposity infl uence these relationships.

Details

Metrics

54 File views/ downloads
747 Record Views
Logo image