A green algae mixture of Scenedesmus and Schroederiella attenuates obesity-linked metabolic syndrome in rats

S A Kumar; M Magnusson; L C Ward; Nicholas A Paul; L Brown

doi:10.3390/nu7042771

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A green algae mixture of Scenedesmus and Schroederiella attenuates obesity-linked metabolic syndrome in rats

Journal article

Open access

Peer reviewed

A green algae mixture of Scenedesmus and Schroederiella attenuates obesity-linked metabolic syndrome in rats

S A Kumar, M Magnusson, L C Ward, Nicholas A Paul and L Brown

Nutrients, Vol.7(4), pp.2771-2787

2015

DOI: https://doi.org/10.3390/nu7042771

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Abstract

visceral obesity

metabolic symptoms

microalgae

insoluble fibre

This study investigated the responses to a green algae mixture of Scenedesmus dimorphus and Schroederiella apiculata (SC) containing protein (46.1% of dry algae), insoluble fibre (19.6% of dry algae), minerals (3.7% of dry algae) and omega-3 fatty acids (2.8% of dry algae) as a dietary intervention in a high carbohydrate, high fat diet-induced metabolic syndrome model in four groups of male Wistar rats. Two groups were fed with a corn starch diet containing 68% carbohydrates as polysaccharides, while the other two groups were fed a diet high in simple carbohydrates (fructose and sucrose in food, 25% fructose in drinking water, total 68%) and fats (saturated and trans fats from beef tallow, total 24%). High carbohydrate, high fat-fed rats showed visceral obesity with hypertension, insulin resistance, cardiovascular remodelling, and nonalcoholic fatty liver disease. SC supplementation (5% of food) lowered total body and abdominal fat mass, increased lean mass, and attenuated hypertension, impaired glucose and insulin tolerance, endothelial dysfunction, infiltration of inflammatory cells into heart and liver, fibrosis, increased cardiac stiffness, and nonalcoholic fatty liver disease in the high carbohydrate, high fat diet-fed rats. This study suggests that the insoluble fibre or protein in SC helps reverse diet-induced metabolic syndrome. © 2015, by the authors; licensee MDPI, Basel, Switzerland.

Details

Title: A green algae mixture of Scenedesmus and Schroederiella attenuates obesity-linked metabolic syndrome in rats
Authors: S A Kumar (Author) - University of Southern Queensland
M Magnusson (Author) - James Cook University
L C Ward (Author) - University of Queensland
Nicholas A Paul (Author) - James Cook University
L Brown (Author) - University of Southern Queensland
Publication details: Nutrients, Vol.7(4), pp.2771-2787
Publisher: MDPI AG
Date published: 2015
DOI: 10.3390/nu7042771
ISSN: 2072-6643; 2072-6643
Copyright note: Copyright © 2015 The authors. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
Organisation Unit: School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering
Language: English
Record Identifier: 99450934502621
Output Type: Journal article
Research Statement: false

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Collaboration types: Domestic collaboration
Web Of Science research areas: Nutrition & Dietetics

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