Naseseazine C, a new anti-plasmodial dimeric diketopiperazine from a marine sediment derived Streptomyces sp.

Larissa Buedenbender; Tanja Grkovic; Sandra Duffy; D Ipek Kurtboke; Vicky M Avery; Anthony R Carroll

doi:10.1016/j.tetlet.2016.11.071

Naseseazine C, a new anti-plasmodial dimeric diketopiperazine from a marine sediment derived Streptomyces sp.

Larissa Buedenbender, Tanja Grkovic, Sandra Duffy, D Ipek Kurtboke, Vicky M Avery Anthony R Carroll

Tetrahedron Letters, Vol.57(52), pp.5893-5895

2016

: https://doi.org/10.1016/j.tetlet.2016.11.071

marine streptomyces species

naseseazines

diketopiperazines

anti-plasmodial

A new dimeric diketopiperazine, naseseazine C, and the known naseseazines A and B were isolated from solid culture extracts of an Australian marine sediment derived Streptomyces species. Naseseazine C displayed a new C-6â€²/C-3 linkage between the two diketopiperazine subunits and showed moderate activity against the chloroquine-sensitive malaria parasite, Plasmodium falciparum (3D7 strain).

: Naseseazine C, a new anti-plasmodial dimeric diketopiperazine from a marine sediment derived Streptomyces sp.
: Larissa Buedenbender (Author) - Griffith University
Tanja Grkovic (Author) - Griffith University
Sandra Duffy (Author) - Griffith University
D Ipek Kurtboke (Author) - University of the Sunshine Coast
Vicky M Avery (Author) - Griffith University
Anthony R Carroll (Corresponding Author) - Griffith University
: Tetrahedron Letters, Vol.57(52), pp.5893-5895
: Elsevier Ltd
: 2016
: 10.1016/j.tetlet.2016.11.071
: 0040-4039; 1873-3581
: Screening platforms for malaria drug discovery: identification of new therapeutics, LP120200557, Australian Research Council (Australia, Canberra) - ARC
: School of Science and Engineering - Legacy; GeneCology Research Centre - Legacy; School of Science, Technology and Engineering
: English
: 99450578402621
: Journal article

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