Thermoregulatory responses to combined moderate heat stress and hypoxia

D A Low; Tom G Bailey; N Timothy Cable; H Jones

doi:10.1111/micc.12297

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Thermoregulatory responses to combined moderate heat stress and hypoxia

Journal article

Open access

Peer reviewed

Thermoregulatory responses to combined moderate heat stress and hypoxia

D A Low, Tom G Bailey, N Timothy Cable and H Jones

Microcirculation, Vol.23(7), pp.487-494

2016

DOI: https://doi.org/10.1111/micc.12297

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Abstract

Medical and Health Sciences

cutaneous blood flow

hyperthermia

hypoxia

sweating

OBJECTIVE: The aim of this study was to examine the cutaneous vascular and sudomotor responses to combined moderate passive heat stress and normobaric hypoxia. METHOD: Thirteen healthy young males, dressed in a water-perfused suit, underwent passive heating (Δcore temperature ~0.7°C) twice (Normoxia; 20.9% O2 and Hypoxia; 13% O2 ). Chest and forearm skin blood flow (SkBF; laser-Doppler flux) and sweat rate (SR; capacitance hygrometry), core (intestinal pill), and skin temperatures, were recorded. RESULTS: Hypoxia reduced baseline oxygen saturation (98±1 vs 89±6%, P<.001) and elevated chest (P=.03) and forearm SkBF (P=.03), and HR (64±9 vs 69±8 beats.min-1 , P<.01). During heating, mean body temperature (T¯BODY) thresholds for SkBF (P=.41) and SR (P=.28) elevations were not different between trials. The SkBF: T¯BODY linear sensitivity during the initial phase of heating was lower at the chest (P=.035) but not different at the forearm (P=.17) during hypoxia. With increasing levels of heating chest SkBF was not different (P=.55) but forearm SkBF was lower (P<.01) during hypoxia. Chest (P=.85) and forearm (P=.79) SR: T¯BODY linear sensitivities were not different between trials. CONCLUSION: While sudomotor responses and the initiation of cutaneous blood flow elevations are unaffected, hypoxia differentially effects regional SkBF responses during moderate passive heating.

Details

Title: Thermoregulatory responses to combined moderate heat stress and hypoxia
Authors: D A Low (Author) - Liverpool John Moores University, United Kingdom
Tom G Bailey (Author) - Liverpool John Moores University, United Kingdom
N Timothy Cable (Author) - Liverpool John Moores University, United Kingdom
H Jones (Author) - Liverpool John Moores University, United Kingdom
Publication details: Microcirculation, Vol.23(7), pp.487-494
Publisher: John Wiley & Sons Ltd.
Date published: 2016
DOI: 10.1111/micc.12297
ISSN: 1073-9688
Copyright note: Copyright © 2016. This is the accepted version of the following article: Low, D A; Bailey, Tom G; Cable, Timothy N; Jones, H (2016) Thermoregulatory responses to combined moderate heat stress and hypoxia, Microcirculation, 23:7, pp.487-494, which has been published in final form at http://dx.doi.org/10.1111/micc.12297
Organisation Unit: UniSC Clinical Trials Centre; University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy
Language: English
Record Identifier: 99450462802621
Output Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Hematology; Peripheral Vascular Disease

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Source: InCites