Abnormal Right Ventricular Tissue Velocities After Repair of Congenital Heart Disease-Implications for Late Outcomes

R Puranik; Kim Greaves; R E Hawker; L A Pressley; P J Robinson; D S Celermajer

doi:10.1016/j.hlc.2007.02.084

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Abnormal Right Ventricular Tissue Velocities After Repair of Congenital Heart Disease-Implications for Late Outcomes

Journal article

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Abnormal Right Ventricular Tissue Velocities After Repair of Congenital Heart Disease-Implications for Late Outcomes

R Puranik, Kim Greaves, R E Hawker, L A Pressley, P J Robinson and D S Celermajer

Heart, Lung and Circulation, Vol.16(4), pp.295-299

2007

DOI: https://doi.org/10.1016/j.hlc.2007.02.084

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Abstract

myocardial velocity

congenital heart disease

right ventricle

Background: Although repair of Tetralogy of Fallot (TOF) and transposition of the great arteries (TGA) has facilitated survival into adulthood, many survivors have residual haemodynamic abnormalities, including exercise intolerance and late right ventricular (RV) failure. Methods: We studied 40 asymptomatic adult subjects (31.3±1.5 years) after congenital heart disease (CHD) surgery during childhood, using tissue Doppler echocardiography (TDE). We compared systolic (S?) and diastolic (E? for early filling) RV and LV velocities, with 40 age matched controls (29.5±1.0 years). Results: Both RV S? and E? velocities were significantly slower in the CHD group compared to controls (6.3±0.4 cm/s vs. 9.3±0.3 cm/s; 8.5±0.5 cm/s vs. 10.9±0.4 cm/s, respectively, p < 0.001 for both). By contrast, LV S? and E? velocities were similar in both groups. Interestingly, in 50% of CHD subjects where RV function was reported as 'normal', both RV S? and E? velocities were significantly slower compared with controls (6.5±0.6 cm/s vs. 9.3±0.3 cm/s, p < 0.0001 and 9.4±0.7 cm/s vs. 10.9±0.4 cm/s, p < 0.05 respectively). Conclusions: RV S? and E? velocities are frequently abnormal in asymptomatic survivors of TOF and TGA repair, even where RV function appears 'normal'. Hence TDE during follow up may be a sensitive means of detecting pre-clinical abnormalities in RV performance. © 2007 Australasian Society of Cardiac and Thoracic Surgeons and the Cardiac Society of Australia and New Zealand.

Details

Title: Abnormal Right Ventricular Tissue Velocities After Repair of Congenital Heart Disease-Implications for Late Outcomes
Authors: R Puranik (Author) - Royal Prince Alfred Hospital
Kim Greaves (Author) - Royal Prince Alfred Hospital
R E Hawker (Author) - Royal Prince Alfred Hospital
L A Pressley (Author) - Royal Prince Alfred Hospital
P J Robinson (Author) - Royal Prince Alfred Hospital
D S Celermajer (Author) - Royal Prince Alfred Hospital
Publication details: Heart, Lung and Circulation, Vol.16(4), pp.295-299
Publisher: Elsevier Australia
DOI: 10.1016/j.hlc.2007.02.084
ISSN: 1443-9506
Organisation Unit: Faculty of Science, Health, Education and Engineering; University of the Sunshine Coast, Queensland
Language: English
Record Identifier: 99450186402621
Output Type: Journal article

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