${session.getAttribute("locale")} 5 Lower In vivo Myo-Inositol in the Anterior Cingulate Cortex Correlates with Delayed Melatonin Rhythms in Young Persons with Depression Wed 27 Nov 2019 14:16:55 AEST ]]> Response to Dr Fried & Dr Kievit, and Dr Malhi et al Wed 27 Nov 2019 13:55:45 AEST ]]> Subcortical brain structure and suicidal behaviour in major depressive disorder: A meta-analysis from the ENIGMA-MDD working group Wed 27 Nov 2019 12:59:39 AEST ]]> P.3.14 Brain structural correlates of insomnia severity in major depressive disorder: Results from the ENIGMA-MDD consortium Wed 26 Jun 2019 12:07:39 AEST ]]> Peripheral nerve diffusion tensor imaging is reliable and reproducible Wed 20 Jun 2018 13:35:51 AEST ]]> The Long-Term Efficacy of Suicide Prevention Gatekeeper Training: A Systematic Review Wed 18 Dec 2019 15:25:45 AEST ]]> Brain GABA levels are reduced in alcoholic liver disease: A proton magnetic resonance spectroscopy study Wed 18 Dec 2019 13:47:49 AEST ]]> Aerobic exercise intervention in young people with schizophrenia spectrum disorders; improved fitness with no change in hippocampal volume Wed 17 Aug 2016 11:44:39 AEST ]]> Episodic memory in depression: The unique contribution of the anterior caudate and hippocampus Wed 15 Feb 2017 15:11:04 AEST ]]> Utility of the cumulative stress and mismatch hypotheses in understanding the neurobiological impacts of childhood abuse and recent stress in youth with emerging mental disorder Wed 14 Mar 2018 12:51:39 AEST ]]> Peripheral nerve diffusion tensor imaging as a measure of disease progression in ALS Wed 14 Mar 2018 11:34:42 AEST ]]> Microstructural white matter tract alteration in Prader-Willi syndrome: A diffusion tensor imaging study Wed 13 Dec 2017 10:43:54 AEST ]]> Decoding diffusivity in multiple schlerosis: analysis of optic radiation lesional and non-lesional white matter Wed 12 Feb 2020 14:25:37 AEST ]]> Cognitive dysfunction and functional disability in alcohol-dependent adults with or without a comorbid affective disorder Wed 08 Nov 2017 16:05:56 AEST ]]> Effect of Weight Loss via Severe vs Moderate Energy Restriction on Lean Mass and Body Composition Among Postmenopausal Women With Obesity: The TEMPO Diet Randomized Clinical Trial Wed 08 Jan 2020 09:49:44 AEST ]]> Determining the benefits of transcranial direct current stimulation (tDCS) on functional upper limb movement in chronic stroke 0.05). When the data were analysed according to disability, participants with moderate/severe disability showed significantly improved gross motor function following cathodal stimulation compared with sham (P=0.014). However, this was accompanied by decreased key grip strength in the unaffected hand (P=0.003). We are unable to endorse the use of anodal and cathodal tDCS in the management of upper limb dysfunction in chronic stroke patients. Although there appears to be more potential for the use of cathodal stimulation in patients with severe disability, the effects were small and must be considered with caution as they were accompanied by unanticipated effects in the unaffected upper limb.]]> Wed 06 Sep 2017 10:50:09 AEST ]]> Elevated levels of GABA+ in migraine detected using 1H-MRS Wed 06 Apr 2016 15:23:46 AEST ]]> Cluster analysis reveals abnormal hippocampal neurometabolic profiles in young people with mood disorders Wed 06 Apr 2016 11:32:46 AEST ]]> P300 event-related potentials in children with dyslexia Wed 05 Apr 2017 15:21:34 AEST ]]> The longitudinal relationship between anterior cingulate glutathione and executive functioning in individuals at risk for dementia: a magnetic resonance spectroscopy study 12 months. Results: Of the data currently available, the mean time between baseline and follow-up assessment was 3.5 years (SD=1.2 years) and mean age at baseline assessment was 64.6 years (SD=9.6 years). Overall, change in GSH/Cr correlated significantly with change in performance on the TMT-B (r=0.58, p=0.024). Conclusions: This study will be the largest to examine the longitudinal relationship between oxidative stress status and cognitive functioning in a cohort ‘at-risk’ for dementia. Preliminary outcomes show that an increase in GSH is associated with improved executive functioning over a 3.5 year period. This data has important implications for the prevention of cognitive decline and dementia, with intervention studies aimed at supporting antioxidant defenses and optimizing the redox state of cells now warranted.]]> Wed 04 Apr 2018 11:48:39 AEST ]]> A novel task-oriented brain computer interface for human-robot interaction Tue 25 Jun 2019 13:50:39 AEST ]]> Response to Dr Fried & Dr Kievit, and Dr Malhi et al. [Size matters; but so does what you do with it!] Tue 25 Jun 2019 13:15:39 AEST ]]> Stress, trauma and synaptic plasticity Tue 25 Jun 2019 12:47:39 AEST ]]> Structural and functional connectivity underlying grey matter covariance: impact of developmental insult Tue 25 Jun 2019 10:17:29 AEST ]]> Stimulating Young Minds: Investigating a Next Generation Treatment for Depression in Youth .05). Greater improvements in depressive symptoms were associated with better pre-treatment set-shifting performance (p&.05; r=.53). In patients with moderate-severe depression (n=9), greater improvements in psychiatric symptoms were associated with later age of illness onset (p&.05; r=.88). Conclusions: In keeping with the literature, rTMS improves depressive, anxiety and psychiatric symptoms in young people. These data suggest that cognition may have utility in predicting rTMS treatment response and targeting rTMS earlier in the course of illness may result in better response outcomes in young people with depression.]]> Tue 24 Apr 2018 16:04:49 AEST ]]> Healthy aging affects cerebrovascular reactivity and pressure-flow responses, but not neurovascular coupling: A cross-sectional study Tue 21 May 2019 14:10:48 AEST ]]> White matter integrity alterations in post-traumatic stress disorder Tue 20 Nov 2018 15:26:31 AEST ]]> Hippocampal development in youth with a history of childhood maltreatment Tue 20 Mar 2018 13:52:39 AEST ]]> Subcortical volumetric differences between clinical stages of young people with affective and psychotic disorders Tue 18 Jun 2019 14:19:01 AEST ]]> How Surfing Could be a Treatment for Mental Illness Tue 18 Jun 2019 09:52:42 AEST ]]> Sports are good for your mood, but concussion is not Tue 18 Jun 2019 09:52:39 AEST ]]> Resting State EEG Hemispheric Power Asymmetry in Childrem with Dyslexia Tue 17 May 2016 16:24:21 AEST ]]> Concussion risk and suicide prevention: Balancing the risks and benefits of youth sport Tue 15 Oct 2019 15:31:39 AEST ]]> Alliance against depression and suicide: Gatekeeper training, engagement, and retention in a regional community Tue 15 Jan 2019 09:07:37 AEST ]]> Impaired causal awareness and associated cortical–basal ganglia structural changes in youth psychiatric disorders Tue 14 Feb 2017 15:35:27 AEST ]]> A data-driven transdiagnostic analysis of white matter integrity in young adults with major psychiatric disorders Tue 11 Sep 2018 13:13:24 AEST ]]> Elucidating the neurobiology of cyberbullying using functional Magnetic Resonance Imaging (fMRI): A hypothesis Tue 11 Feb 2020 16:11:36 AEST ]]> Sleep-wake, cognitive and clinical correlates of treatment outcome with repetitive transcranial magnetic stimulation for young adults with depression Tue 11 Dec 2018 10:16:00 AEST ]]> Paroxysmal dyskinesias with drowsiness and thalamic lesions in GABA transaminase deficiency Tue 10 Mar 2020 13:57:23 AEST ]]> Sleep Disturbance in Mild Cognitive Impairment Is Associated With Alterations in the Brain's Default Mode Network Tue 10 Mar 2020 13:29:19 AEST ]]> Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group Tue 10 Mar 2020 11:30:25 AEST ]]> A model of amygdala function following plastic changes at specific synapses during extinction Tue 09 Apr 2019 10:46:49 AEST ]]> A systematic review and meta-analysis of magnetic resonance imaging measurement of structural volumes in posttraumatic stress disorder Tue 05 Apr 2016 10:20:45 AEST ]]> Reduced gamma-aminobutyric acid is associated with emotional and behavioral problems in Prader–Willi syndrome Tue 04 Apr 2017 13:27:40 AEST ]]> Early intervention, Prevention and Prediction in Clinical Psychiatry Tue 02 Jul 2019 08:49:39 AEST ]]> Brain Aging in Major Depressive Disorder: Results from the ENIGMA Major Depressive Disorder working group Thu 27 Jun 2019 15:25:40 AEST ]]> Emotional processing, P50 sensory gating, and social functioning in bipolar disorder Thu 24 May 2018 13:44:50 AEST ]]> Subcortical Volume Correlates of Psychological Distress in Early Adolescence Thu 19 Mar 2020 13:40:21 AEST ]]> Effect of aerobic exercise on hippocampal volume in humans: A systematic review and meta-analysis Thu 19 Apr 2018 16:43:59 AEST ]]> In vivo imaging of oxidative stress and fronto-limbic white matter integrity in young adults with mood disorders Thu 19 Apr 2018 16:29:53 AEST ]]> Neurometabolite levels in alcohol use disorder patients during baclofen treatment and prediction of relapse to heavy drinking Thu 06 Sep 2018 09:54:27 AEST ]]> Elucidating the glutamatergic processes underlying mismatch negativity deficits in early stage bipolar disorder and schizophrenia: A combined 1H-MRS and EEG study Thu 04 Apr 2019 14:34:44 AEST ]]> In vivo imaging of oxidative stress and white matter integrity in fronto-limbic structural connectivity in young adults with major depression and bipolar disorder Thu 03 Oct 2019 10:06:58 AEST ]]> Neurobiological correlates of a clinical staging model in youth mental health Thu 03 Oct 2019 10:06:46 AEST ]]> Axonal conduction in multiple sclerosis: A combined magnetic resonance imaging and electrophysiological study of the medial longitudinal fasciculus Mon 27 Jun 2016 11:19:52 AEST ]]> Cortical network models of impulse firing in the resting and active states predict cortical energetics Mon 27 Jun 2016 10:09:52 AEST ]]> Is the Theta/Beta EEG Marker for ADHD Inherently Flawed? Mon 27 Aug 2018 13:46:24 AEST ]]> Mindfulness Induces Changes in Anterior Alpha Asymmetry in Healthy Older Adults Mon 24 Jun 2019 15:54:39 AEST ]]> Using measures of intrinsic homeostasis and extrinsic modulation to evaluate mental health in adolescents: Preliminary results from the Longitudinal Adolescent Brain Study (LABS) Mon 24 Feb 2020 12:38:30 AEST ]]> Brain N-Acetyl Aspartate and associations with cognitive impairment in alcohol dependent patients Mon 24 Feb 2020 12:38:27 AEST ]]> Anorexia nervosa, zinc deficiency and the glutamate system: The ketamine option Mon 23 Mar 2020 10:53:23 AEST ]]> Pineal volume and evening melatonin in young people with affective disorders Mon 18 Dec 2017 10:04:55 AEST ]]> Type-specific effects of childhood maltreatment on adult sleep problems Mon 17 Feb 2020 16:41:46 AEST ]]> Stimulating young minds: Investigating a next generation treatment for depression in youth .05). Greater improvements in depressive symptoms were associated with better pre-treatment set-shifting performance (p<.05; r=.53). In patients with moderate-severe depression (n=9), greater improvements in psychiatric symptoms were associated with later age of illness onset (p<.05; r=.88). Conclusion: In keeping with the literature, rTMS improves depressive, anxiety and psychiatric symptoms in young people. These data suggest that cognition may have utility in predicting rTMS treatment response and targeting rTMS earlier in the course of illness may result in better response outcomes in young people with depression.]]> Mon 17 Feb 2020 16:20:37 AEST ]]> Biomarkers of Neurodegeneration in Multiple Sclerosis Mon 17 Feb 2020 15:03:37 AEST ]]> Wallerian Degeneration in the Corticospinal Tract Following Tumefactive Demyelination: Conventional and Advanced Magnetic Resonance Imaging Mon 06 Feb 2017 16:34:34 AEST ]]> The underlying neurobiology of key functional domains in young people with mood and anxiety disorders: A systematic review Mon 06 Feb 2017 16:27:36 AEST ]]> Microglial cell hyper-ramification and neuronal dendritic spine loss in the hippocampus and medial prefrontal cortex in a mouse model of PTSD Mon 05 Aug 2019 15:39:38 AEST ]]> Cortical GABA levels in alcohol use disorder patients and prediction of relapse to heavy drinking Mon 04 Feb 2019 12:48:03 AEST ]]> Investigating the Links between Adolescent Sleep Deprivation, Fronto-limbic connectivity and the Onset of Mental Disorders: A Review of the Literature Mon 02 Dec 2019 09:31:44 AEST ]]> Nocturnal Hypoxemia Is Associated with Altered Parahippocampal Functional Brain Connectivity in Older Adults at Risk for Dementia Fri 28 Feb 2020 11:50:25 AEST ]]> Understanding heterogeneity in grey matter research of adults with childhood maltreatment—A meta-analysis and review Fri 28 Apr 2017 10:18:21 AEST ]]> The Association Between Clinical Characteristics of Migraine and Brain GABA Levels: An Exploratory Study Fri 28 Apr 2017 10:17:58 AEST ]]> Binge drinking and the young brain: A mini review of the neurobiological underpinnings of alcohol-induced blackout Fri 22 Feb 2019 09:35:43 AEST ]]> Affective Disorders with or Without Comorbid Alcohol Dependence: a Longitudinal Neuropsychological and Neuroimaging Investigation in Young Adults Fri 21 Jun 2019 16:02:57 AEST ]]> An Uncertainty Visual Analytics Framework for fMRI Functional Connectivity Fri 21 Jun 2019 15:34:39 AEST ]]> Interactive impact of childhood maltreatment, depression, and age on cortical brain structure: mega-analytic findings from a large multi-site cohort Fri 21 Jun 2019 15:06:41 AEST ]]> Brain responses to mechanical rectal stimuli in patients with faecal incontinence: an fMRI study Fri 20 Apr 2018 13:50:56 AEST ]]> Functional Connectivity in the Default Mode Network is Reduced in Association with Nocturnal Awakening in Mild Cognitive Impairment Fri 16 Aug 2019 13:49:48 AEST ]]> Volume of Sub-Cortical Structures in Posttraumatic Stress Disorder from Multi-Site Investigation by ENIGMA and PGC Consortia Fri 15 Sep 2017 12:39:54 AEST ]]> Cerebrovascular Correlates of Subclinical Attentional Disturbancesin Non-stroke Cardiovascular Disease  0.6). No significant group differences were observed in N2 latency, P3 amplitude, or P3 latency. Further, MCAv and PI were strongly associated with N2 amplitude in the CVD group, such that greater MCAv was associated with reductions in N2 amplitude (b = −0.58, p = .018), whilst PI was associated with increases in N2 amplitude (b = 0.66, p = .006). No relationships between MCAv or PI with N2 or P3 ERP components were observed in the healthy control group. The data reported here suggest that a reduction in N2 amplitude may be an important objective indicator of subclinical cognitive and attentional alterations in non-stroke CVD, and support the notion that cerebrovascular hemodynamic disturbances play a role in the pathogenesis of cognitive deterioration secondary to non-stroke CVD.]]> Fri 15 Nov 2019 13:38:44 AEST ]]> Associations between Facial Emotion Recognition and Mental Health in Early Adolescence Fri 14 Feb 2020 09:27:22 AEST ]]> Neurobiological underpinnings of cyberbullying: A pilot functional magnetic resonance imaging study Fri 13 Dec 2019 15:21:04 AEST ]]> A Review of Modern Radiation Therapy Dose Escalation in Locally Advanced Head and Neck Cancer Fri 10 Jan 2020 10:58:57 AEST ]]> Anodal direct current stimulation in the healthy aged: Effects determined by the hemisphere stimulated 0.05). This effect occurred irrespective of the hemisphere stimulated. Stimulation did not produce significant effects on measures of gross function, grip strength, reaction times, or electrophysiological measures on the EEG data. Conclusion: This study demonstrated that the hemispheres respond differently to anodal stimulation and the response appears to be task specific but not mediated by age. © 2015 - IOS Press and the authors. All rights reserved.]]> Fri 08 Apr 2016 13:22:44 AEST ]]> Association of Anterior Cingulate Glutathione with Sleep Apnea in Older Adults at-risk for Dementia Fri 08 Apr 2016 11:58:46 AEST ]]> On the origins of the 'global signal' determined by functional magnetic resonance imaging in the resting state Fri 08 Apr 2016 11:25:48 AEST ]]> Cortical network models of firing rates in the resting and active states predict bold responses Fri 08 Apr 2016 08:11:11 AEST ]]> Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group Fri 07 Feb 2020 16:49:43 AEST ]]> Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group 21 years). Compared to matched controls, adolescents with MDD had lower total surface area (but no differences in cortical thickness) and regional reductions in frontal regions (medial OFC and superior frontal gyrus) and primary and higher-order visual, somatosensory and motor areas (d: −0.26 to −0.57). The strongest effects were found in recurrent adolescent patients. This highly powered global effort to identify consistent brain abnormalities showed widespread cortical alterations in MDD patients as compared to controls and suggests that MDD may impact brain structure in a highly dynamic way, with different patterns of alterations at different stages of life.Molecular Psychiatry advance online publication, 3 May 2016; doi:10.1038/mp.2016.60. © 2016 Macmillan Publishers Limited]]> Fri 07 Feb 2020 16:21:49 AEST ]]> Mental Training Affects Electrophysiological Markers of Attention Resource Allocation in Healthy Older Adults Fri 07 Feb 2020 13:47:47 AEST ]]> Current sleep disturbance in older people with a lifetime history of depression is associated with increased connectivity in the Default Mode Network 5. A total of 68% (n=48) of cases with a lifetime history of depression met criteria for sleep-disturbance. DMN functional connectivity was assessed via ROI-to-ROI analyses. Results: Relative to controls, those with lifetime major depression demonstrated significantly increased functional connectivity between the ventromedial prefrontal cortex and the temporal pole. Within the depression group (n = 48), those with current sleep disturbance had significantly increased connectivity between the anterior medial prefrontal cortex and both the parahippocampal cortex and the hippocampal formation, relative to those without sleep disturbance (n = 23). These results were present after controlling for MCI diagnosis. Conclusions: Current sleep disturbance together with depression is associated with distinct abnormalities in DMN functioning incorporating regions responsible for self-reflection and declarative memory processes. Impaired sleep is associated with increased connectivity between these regions. Future studies may augment these findings with complementary imaging techniques including cortical thickness and diffusion tensor imaging, as well as high density electroencephalogram recording.]]> Fri 07 Feb 2020 13:33:53 AEST ]]> Frontal and subcortical grey matter reductions in PTSD Fri 07 Feb 2020 13:20:36 AEST ]]> Smaller Hippocampal Volume in Posttraumatic Stress Disorder: A Multisite ENIGMA-PGC Study: Subcortical Volumetry Results From Posttraumatic Stress Disorder Consortia Fri 07 Feb 2020 13:19:41 AEST ]]> Childhood adversity impacts on brain subcortical structures relevant to depression Fri 07 Feb 2020 13:13:02 AEST ]]> Regulation of fear extinction by long-term depression: the roles of endocannabinoids and brain derived neurotrophic factor Fri 07 Feb 2020 13:06:09 AEST ]]> Behavior, Neuropsychology and fMRI Fri 07 Feb 2020 12:58:49 AEST ]]> Alcohol use in bipolar disorder: A neurobiological model to help predict susceptibility, select treatments and attenuate cortical insult Fri 07 Feb 2020 12:52:29 AEST ]]> A longitudinal proton magnetic resonance spectroscopy study investigating oxidative stress as a result of alcohol and tobacco use in youth with bipolar disorder Fri 07 Feb 2020 12:52:16 AEST ]]> Stress, trauma and PTSD: translational insights into the core synaptic circuitry and its modulation Fri 01 Jul 2016 11:34:46 AEST ]]>