http://research.usc.edu.au/vital/access/manager/Index ${session.getAttribute("locale")} 5 iCanADAPT Early protocol: Randomised controlled trial (RCT) of clinician supervised transdiagnostic internet-delivered cognitive behaviour therapy (iCBT) for depression and/or anxiety in early stage cancer survivors -vs- treatment as usual http://research.usc.edu.au/vital/access/manager/Repository/usc:28995 0.6, power of 80%, and alpha at.05), but 10% more will be recruited to account for attrition. A solitary or cumulative diagnosis(es) of Major Depressive Episode (current), Generalised Anxiety Disorder, Illness Anxiety Disorder, Panic Disorder, Agoraphobia, and/or Adjustment disorder will be determined using modules from the Anxiety Disorders Interview Schedule for DSM-5. Depression and anxiety levels with be measured via the total score of the Hospital Anxiety and Depression scale (HADS-T), the primary outcome measure. Secondary measures will include the Kessler 10 to measure general distress, the Fear of Cancer Recurrence Inventory (FCRI) to measure the specific fear of cancer recurrence and the Functional Assessment of Cancer Therapy, General Version 4 (FACT-G) for self-report of physical, social, emotional and functional well-being. iCBT participants will complete the measures before lessons 1 and 5, at post-treatment and at 3-month follow-up. The TAU group will complete similar measures at weeks 1, 8 and 16 of the waiting period. Program efficacy will be determined using intent-to-treat mixed models. Maintenance of gains will be assessed at 3-month follow-up. Mediation analyses using PROCESS will be used to examine the association between change in depressive and anxious symptoms over time and changes in FCRI and FACT-G QOL in separate analysis. Discussion: This is the first RCT looking at iCBT specifically for clinical depression and/or anxiety in a cancer population. Findings will help to direct the role of iCBT in streamlined psycho-social care pathways. Trial registration: Australian New Zealand Clinical Trials Registry: ACTRN12616000231448, registered 19 th February 2016 ( www.anzctr.org.au ). This trial protocol is in compliance with the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) guidelines. © 2017 The Author(s).]]> Tue 25 Jun 2019 13:01:45 AEST ]]> Correction to: iCanADAPT early protocol: Randomised controlled trial (RCT) of clinician supervised transdiagnostic internet-delivered cognitive behaviour therapy (iCBT) for depression and/or anxiety in early stage cancer survivors -vs- treatment as usual. [BMC Cancer., 17, (2017) (193)] DOI: 10.1186/s12885-017-3182-z http://research.usc.edu.au/vital/access/manager/Repository/usc:28996 Tue 25 Jun 2019 13:01:41 AEST ]]> Internet cognitive-behavioural treatment for panic disorder: Randomised controlled trial and evidence of effectiveness in primary care http://research.usc.edu.au/vital/access/manager/Repository/usc:28997 Tue 25 Jun 2019 13:01:41 AEST ]]> Acceptability of an internet cognitive behavioural therapy program for people with early-stage cancer and cancer survivors with depression and/or anxiety: thematic findings from focus groups http://research.usc.edu.au/vital/access/manager/Repository/usc:28993 Tue 25 Jun 2019 12:47:39 AEST ]]> On giving offence: sexuality and psychosis in a forensic setting http://research.usc.edu.au/vital/access/manager/Repository/usc:13068 Fri 07 Nov 2014 14:51:00 AEST ]]>