${session.getAttribute("locale")} 5 Effects of exercise intensity and cardiorespiratory fitness on the acute response of arterial stiffness to exercise in older adults Wed 22 May 2019 16:24:40 AEST ]]> Arterial Stiffness and Abdominal Aortic Aneurysm: The effect of acute exercise 50%. AAA accounts for approximately 2% of all deaths worldwide (Upchurch and Schaub 2006). Surgical repair is the only current treatment option but only available for patients with large AAA (≥55mm) (Nordon, Hinchliffe et al. 2011) leaving patients with small AAA (≤55 mm) with no treatment options. Increased arterial stiffness is a key factor characterising the development and growth of an AAA (Raaz, Zollner et al. 2015) and likely contributes to elevated cardiovascular mortality in patients with small AAA (Golledge, Muller et al. 2006, Bath, Gokani et al. 2015). Therefore, arterial stiffness could be used as an important treatment target in order to delay aneurysm progression and reduce cardiovascular risk. Arterial stiffness is reduced with increased cardiorespiratory fitness (Gando, Murakami et al. 2016) and aerobic-exercise training in older adults (Fujie, Sato et al. 2014). These adaptations are attributed to the frequent, repetitive haemodynamic perturbations associated with each bout of exercise (Green, Hopman et al. 2017). A single bout of exercise transiently lowers arterial stiffness in healthy adults (Kingwell, Berry et al. 1997, Mutter, Cooke et al. 2017), is commonly accompanied by short-term improvements in arterial function and central blood pressure (Millen, Woodiwiss et al. 2016) and may be dependent on exercise intensity (Tordi, Mourot et al. 2010). However, in adults with cardiovascular comorbidities commonly observed in patients with AAA, excessive increases in arterial stiffness during and after exercise (Shim, Yang et al. 2011, Gkaliagkousi, Gavriilaki et al. 2014, Bunsawat, Ranadive et al. 2017) may transiently exacerbate cardiovascular risk (Schultz, La Gerche et al. 2017). To date, little is known about the haemodynamic effects of acute exercise in patients with AAA. Determining the arterial stiffness response to exercise would provide better understanding of the short-term risks and benefits of exercise in patents with AAA, and an insight into the potential efficacy of exercise for reducing arterial stiffness and cardiovascular risk. Hence, this thesis aimed to determine the effect of a single bout of exercise on the post-exercise arterial stiffness response between patients with AAA and healthy older adults. As patients with AAA are older and with low levels of cardiorespiratory fitness, this thesis also explored the effects of cardiorespiratory fitness and exercise intensity on post-exercise arterial stiffness, in healthy older adults. Additionally, this thesis aimed to establish the reliability of its measurements by assessing the reliability of post-exercise changes in arterial stiffness in older healthy adults.]]> Wed 17 Oct 2018 12:48:45 AEST ]]> n-3 PUFAs improve erythrocyte fatty acid profile in patients with small abdominal aortic aneurysms: a randomised controlled trial Wed 06 Nov 2019 12:38:40 AEST ]]> Fitness modulates conduit artery flow-mediated dilation following high- but not moderate­ intensity exercise in the elderly Tue 16 Oct 2018 12:39:10 AEST ]]> Suppressed oxidative stress response in abdominal aortic aneurysm macrophages exposed to lipopolysaccharide Tue 16 Oct 2018 12:38:41 AEST ]]> Cardiorespiratory fitness modulates the acute flow-mediated dilation response following high-intensity but not moderate-intensity exercise in elderly men Tue 16 Oct 2018 12:09:19 AEST ]]> Small Abdominal Aortic Aneurysm is Associated With Endotoxin Tolerant-Like Macrophage Immunosuppression and Decreased Levels of the Resolution-Directed Mediator PGE2 Tue 16 Oct 2018 11:32:51 AEST ]]> Cytokine Responses to Acute Exercise in Healthy Older Adults: The Effect of Cardiorespiratory Fitness Tue 16 Oct 2018 11:23:06 AEST ]]> The effect of exercise intensity on the inflammatory response to acute exercise in older people Tue 16 Jul 2019 09:24:44 AEST ]]> Aortic and Systemic Arterial Stiffness Responses to Acute Exercise in Patients With Small Abdominal Aortic Aneurysms Tue 05 Nov 2019 09:41:43 AEST ]]> Reliability of arterial stiffness indices at rest and following a single bout of moderate‐intensity exercise in older adults Tue 04 Jun 2019 12:40:19 AEST ]]> Omega-3 fatty acids decrease oxidative stress and inflammation in macrophages from patients with small abdominal aortic aneurysm Thu 19 Sep 2019 07:46:53 AEST ]]> Effects of acute exercise on endothelial function in abdominal aortic aneurysm patients Fri 30 Nov 2018 15:04:32 AEST ]]> Acute Inflammatory Responses to Exercise in Patients with Abdominal Aortic Aneurysm Fri 09 Aug 2019 14:45:47 AEST ]]>