http://research.usc.edu.au/vital/access/manager/Index ${session.getAttribute("locale")} 5 Structural brain alterations in major depression: findings from the ENIGMA Major Depressive Disorder Working Group http://research.usc.edu.au/vital/access/manager/Repository/usc:29009 Tue 25 Jun 2019 13:50:40 AEST ]]> Response to Dr Fried & Dr Kievit, and Dr Malhi et al. [Size matters; but so does what you do with it!] http://research.usc.edu.au/vital/access/manager/Repository/usc:28998 Tue 25 Jun 2019 13:15:39 AEST ]]> Response to Dr Fried & Dr Kievit, and Dr Malhi et al http://research.usc.edu.au/vital/access/manager/Repository/usc:19141 Thu 13 Jul 2017 11:07:51 AEST ]]> Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group http://research.usc.edu.au/vital/access/manager/Repository/usc:22024 21 years). Compared to matched controls, adolescents with MDD had lower total surface area (but no differences in cortical thickness) and regional reductions in frontal regions (medial OFC and superior frontal gyrus) and primary and higher-order visual, somatosensory and motor areas (d: −0.26 to −0.57). The strongest effects were found in recurrent adolescent patients. This highly powered global effort to identify consistent brain abnormalities showed widespread cortical alterations in MDD patients as compared to controls and suggests that MDD may impact brain structure in a highly dynamic way, with different patterns of alterations at different stages of life.Molecular Psychiatry advance online publication, 3 May 2016; doi:10.1038/mp.2016.60. © 2016 Macmillan Publishers Limited]]> Mon 29 May 2017 14:02:45 AEST ]]> Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group http://research.usc.edu.au/vital/access/manager/Repository/usc:19142 Fri 01 Jul 2016 11:41:48 AEST ]]>