http://research.usc.edu.au/vital/access/manager/Index ${session.getAttribute("locale")} 5 Variability in clinical outcomes for youth with subthreshold severe mental disorders accessing an early intervention service http://research.usc.edu.au/vital/access/manager/Repository/usc:28858 Tue 25 Jun 2019 11:51:39 AEST ]]> Early intervention, Prevention and Prediction in Clinical Psychiatry http://research.usc.edu.au/vital/access/manager/Repository/usc:29085 Tue 02 Jul 2019 08:49:39 AEST ]]> A longitudinal study of clinical stage transitions among young people presenting to early intervention services with anxiety, mood, or psychotic disorders http://research.usc.edu.au/vital/access/manager/Repository/usc:28839 Mon 24 Jun 2019 11:28:39 AEST ]]> What is the prevalence, and what are the clinical correlates, of insulin resistance in young people presenting for mental health care? A cross-sectional study http://research.usc.edu.au/vital/access/manager/Repository/usc:28841 6.9 mmol/L). By contrast, 9.9% had a HOMA2-IR score >2.0 (suggesting development of IR) and 11.7% (n=90) had a score between 1.5 and 2. Further, there was a positive correlation between BMI and HOMA2-IR (r=0.44, p<0.001). Participants in the upper third of HOMA2-IR scores are characterised by younger age, higher BMIs and depression as a primary diagnosis. HOMA2-IR was predicted by younger age (β=0.19, p<0.001) and higher BMI (β=0.49, p<0.001), together explaining 22% of the variance (F(2,361)=52.1, p<0.001). Conclusions Emerging IR is evident in a significant subgroup of young people presenting to primary care-based mental health services. While the major modifiable risk factor is BMI, a large proportion of the variance is not accounted for by other demographic, clinical or treatment factors. Given the early emergence of IR, secondary prevention interventions may need to commence prior to the development of full-threshold or major mood or psychotic disorders.]]> Mon 17 Jun 2019 15:26:42 AEST ]]>