http://research.usc.edu.au/vital/access/manager/Index ${session.getAttribute("locale")} 5 Effectiveness of SNPs for parentage and sibship assessment in polygamous yellowtail kingfish Seriola lalandi http://research.usc.edu.au/vital/access/manager/Repository/usc:27011 95% were also predicted by DNA microsatellites, i.e. the concordance between SNP and microsatellite pedigrees was high; processing speeds were faster with Sequoia albeit with some minor reductions in accuracy. When parental data were included in the analyses, 98% of the individuals assigned to parents using SNPs were also assigned to the same parents using DNA microsatellites. Overall, the present study provides guidance as to the parameters (minor allele frequencies, number of SNPs, SNP genotyping error rates) that optimize accuracy, and once optimized, SNPs can be used efficiently for sibship and parentage assignments for polygamous species such as yellowtail kingfish in comparison to pedigrees obtained from traditional microsatellite markers.]]> Tue 16 Oct 2018 12:23:25 AEST ]]> Comparative genomics of koala, cattle and sheep strains of Chlamydia pecorum http://research.usc.edu.au/vital/access/manager/Repository/usc:13454 98%. Single nucleotide polymorphisms (SNPs) appear to be key factors in understanding the adaptive process. Two regions of the chromosome were found to be accumulating a large number of SNPs within the koala strains. These regions include the Chlamydia plasticity zone, which contains two cytotoxin genes (toxA and toxB), and a 77 kbp region that codes for putative type III effector proteins. In one koala strain (MC/MarsBar), the toxB gene was truncated by a premature stop codon but is full-length in IPTaLE and DBDeUG. Another five pseudogenes were also identified, two unique to the urogenital strains C. pecorum MC/MarsBar and C. pecorum DBDeUG, respectively, while three were unique to the koala C. pecorum conjunctival isolate IPTaLE. An examination of the distribution of these pseudogenes in C. pecorum strains from a variety of koala populations, alongside a number of sheep and cattle C. pecorum positive samples from Australian livestock, confirmed the presence of four predicted pseudogenes in koala C. pecorum clinical samples. Consistent with our genomics analyses, none of these pseudogenes were observed in the livestock C. pecorum samples examined. Interestingly, three SNPs resulting in pseudogenes identified in the IPTaLE isolate were not found in any other C. pecorum strain analysed, raising questions over the origin of these point mutations. Conclusions: The genomic data revealed that variation between C. pecorum strains were mainly due to the accumulation of SNPs, some of which cause gene inactivation. The identification of these genetic differences will provide the basis for further studies to understand the biology and evolution of this important animal pathogen.]]> Tue 16 Oct 2018 11:20:17 AEST ]]> Association genetics in Corymbia citriodora subsp. variegata identifies single nucleotide polymorphisms affecting wood growth and cellulosic pulp yield http://research.usc.edu.au/vital/access/manager/Repository/usc:7857 Thu 20 Jun 2019 17:03:10 AEST ]]> SNPs in Entire Mitochondrial Genome Sequences (≈15.4 kb) and cox1 Sequences (≈486 bp) Resolve Body and Head Lice From Doubly Infected People From Ethiopia, China, Nepal, and Iran But Not France http://research.usc.edu.au/vital/access/manager/Repository/usc:14135 Mon 15 Jul 2019 15:40:39 AEST ]]> Genetic polymorphisms in the human tissue kallikrein (KLK) locus and their implication in various malignant and non-malignant diseases http://research.usc.edu.au/vital/access/manager/Repository/usc:20318 Mon 11 Sep 2017 12:12:11 AEST ]]> Development of a SNP-based assay for measuring genetic diversity in the Tasmanian devil insurance population http://research.usc.edu.au/vital/access/manager/Repository/usc:19991 Fri 24 Jun 2016 15:53:49 AEST ]]>