This is an introductory article to a collection of themed papers relating to madness as violence of various kinds by people in powerful, often privileged positions, in human organisations. It presents the theoretical framework by outlining how the abuse of power and usually invisible privilege of people in power has maddening effects on subordinate members of an organisation. This is counter-posed with the more conventional understanding of mental illness being about madness and being the preserve of people labelled as mentally ill. Further, spaces and places such as mental hospitals and universities are shown to be containers of systemic violence to the extent there are no proactive efforts to create trauma-informed cultures and workplaces. What counts as madness needs to be reconsidered in light of this collection of papers about this most wicked of problems.